Аннотация:
Разработанные макромолекулярные системы (конъюгаты и полиэлектролитные комплексы) могут быть использованы для защиты организма в случае свободнорадикальной патологии, вызванной радиационным поражением./Taking into account the dependencies found in model synthetic polycations, modification of chitosan was fulfilled. A correlation between the total positive charge of a macro-ion and the polymer efficiency as a bioprotector was found. This study reveals that incorporation of relatively low quantity of plant antioxidant into chitosan side chain, enhance substantial (up to 70-75%) antimutagenic activity of the derived macromolecular systems.
